Building the Neuronal Microtubule Cytoskeleton
نویسندگان
چکیده
منابع مشابه
Building the Neuronal Microtubule Cytoskeleton
Microtubules are one of the major cytoskeletal components of neurons, essential for many fundamental cellular and developmental processes, such as neuronal migration, polarity, and differentiation. Microtubules have been regarded as critical structures for stable neuronal morphology because they serve as tracks for long-distance transport, provide dynamic and mechanical functions, and control l...
متن کاملBuilding the Microtubule Cytoskeleton
The microtubule (MT) cytoskeleton gives cells their shape, organizes the cellular interior, and segregates chromosomes. These functions rely on the precise arrangement of MTs, which is achieved by the coordinated action ofMT-associated proteins (MAPs). We highlight the first andmost important examples of how different MAP activities are combined in vitro to create an ensemble function that exce...
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ژورنال
عنوان ژورنال: Neuron
سال: 2015
ISSN: 0896-6273
DOI: 10.1016/j.neuron.2015.05.046